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Quantitative Lipidomics
Lipids play a crucial role in plant metabolism, serving as structural components of cell membranes, primary storage compounds in seeds, pigments for energy capture in leaves, and signaling molecules for cell communication.
Lipids are essential in the growth, development, and response to environmental changes in plants. Glycerolipids, the most abundant lipids in plants, initiate the perception of environmental stimuli in cell membranes, while phospholipids constitute the fundamental and vital components of cell membranes. Other lipid classes, such as diacylglycerols, phosphatidic acids, phosphatidylinositols, lysophospholipids, and free fatty acids, act as second messengers and play crucial roles in signal transduction during plant growth, development, and stress responses.


Lipids, a vital class of biomolecules in organisms, are insoluble in water and soluble in non-polar organic solvents. They encompass eight major categories: fatty acids, glycerolipids, glycerophospholipids, sphingolipids, sterol lipids, prenol lipids, saccharolipids, and polyketides. Lipids constitute the primary components of cell membranes, serve as important energy sources and signaling molecules, and participate in the regulation of various life activities. Abnormalities in lipid metabolism may lead to various diseases such as obesity, atherosclerosis, and diabetes.


Lipidomics, by studying the composition, structure, and quantification of lipids in biological samples, aims to elucidate the metabolic pathways of lipids. It can be utilized to discover biomarkers and investigate the overall role of lipid molecules in various life phenomena.


Technical Advantages:

  • Absolute quantification of lipids: Precise quantification of 23 classes of lipid substances with 90+ isotopic internal standards.
  • Professional team for detection and analysis: Automated operation through computer programs.


Application Areas:

  • Analysis of changes in lipid composition along different metabolic pathways in various metabolic diseases, revealing the functions and impacts of lipid components during the occurrence and development of related diseases.
  • Investigation of biological functions of lipid components by comparing differences in lipid composition in different treatments of biological samples.
  • Biomarker screening.
  • Identification of differences in lipid composition under different treatments.


Collaborative Case:

  • "Lipidomic insights into the immune response and pearl formation in transplanted pearl oyster Pinctada fucata martensii" published in Frontiers in Immunology (IF=8.786).【Customer Article】
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