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Nanoparticle proteomics
Developed by Seer, Proteograph is an advanced pre-processing solution coupled with high-precision mass spectrometry for unbiased and in-depth protein detection in bodily fluid samples such as serum and plasma.


The Proteograph-DIA proteomics solution includes:

  • Proteograph assay kit
  • SP100 automated workstation
  • Proteograph analysis suite (PAS) data analysis package


This system eliminates the need for additional removal of high-abundance proteins and fully automates the process from raw sample to peptide collection.


The Proteograph assay kit comprises 5 patented Nanoparticle (NPs) magnetic beads and a complete set of reagents and consumables, capable of simultaneously processing 16 samples. With enhanced affinity for low-abundance proteins in bodily fluid samples like plasma, it identifies low-abundance proteins associated with diseases, opening new avenues for exploring protein biomarkers in disease-related plasma and other bodily fluids.


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Technical Advantages:

  • High Depth, Wide Coverage:
    • 5 patented nanomagnetic beads enrich low-abundance proteins with excellent affinity.
    • One-time identification of over 5000 proteins in human plasma.
  • High Throughput, Fast Turnaround:
    • Fully automated pre-processing; from enrichment to peptide segments takes only 7 hours.
    • One-time pre-processing of 16 sample cases.
  • High Quality, High Stability:
    • Automated pre-processing workstation eliminates system errors.
    • Peptide segment coefficient of variation (CV) is below 20%.
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