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Peptidomics

Peptidomics is to study the structure, function, change law and correlation of polypeptide groups based on endogenous peptides and low molecular weight proteins. There is no obvious boundary between polypeptide and protein. It is generally considered that proteins with molecular weight less than 10kDa are called polypeptides. Both peptidomics and proteomics are complementary to genomics. Peptide can reflect the process of protein synthesis, processing and degradation under different physiological and pathological conditions, and regulate the process of gene expression and metabolism. Therefore, peptidomics is considered as a "bridge" between proteomics and metabolomics.


Advantages

High efficiency: improve the efficiency of extracting endogenous peptides from samples

High throughput: study the endogenous peptides of multiple samples at the same time

High specificity: non antibody dependent, no antibody cross reaction

Qualitative and quantitative: realize the qualitative and quantitative analysis of endogenous peptides

Less damage: ensure the naturalness of the extracted peptides

Application

Identification of peptides in cell, tissue and body fluid samples under a certain physiological state.

Neuropeptide / signal peptide research.

Cell antigen epitope prediction.

Development of novel peptide drug precursors.

Biomarker as a new disease.

Natural antibacterial / antiviral peptides.

Study on catalytic reaction of unknown enzymes in vivo.

Finding new functional peptide molecules.

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