- Untargeted Metabolomics
- Lipidomics
- Targeted Metabolomics
- Functional Metabolomics
-
Proteomics
- Nanoparticle proteomics
- iTRAQ/TMT-based Proteomics Analysis
- Label free Quantitative Proteomics
- Protein Identification
- DIA proteomics
- Peptidomics
- Parallel Reaction Monitoring (PRM) Targeted Proteome
- Metpro -Ⅱ Protein-Metabolite Interactions
- Phosphoproteomics
- Acetylation Analysis
- Protein Ubiquitination Analysis
The normal release of neurotransmitters plays a crucial role in maintaining the normal physiological functions of the body, and this phenomenon is observable in animals as well. Sudden stress during slaughter and transportation processes can trigger the release of neurotransmitters in the brain. When neurons are stimulated, hormones are released into the bloodstream, resulting in stimulated muscle metabolism, leading to poor meat quality. It has been demonstrated that animals undergoing stress exhibit lower concentrations of complex amines in the hypothalamus.
Neurotransmitters act on receptors located on the postsynaptic neurons or effector cell membranes, thereby fulfilling their function of information transmission. The normal release of neurotransmitters is essential for maintaining the body's normal physiological functions. Simultaneously, abnormalities in neurotransmitter release and regulation are associated with various pathological processes, such as depression, addiction, Parkinson's disease (PD), and Alzheimer's disease (AD). Therefore, precise analysis and detection of neurotransmitters at the molecular, cellular, and circuit levels can provide a deeper understanding of the pathogenesis of diseases and lay the foundation for the development of clinical drugs.
Neurotransmitters and their metabolites are widely distributed in the central and peripheral nervous systems, playing a crucial role in maintaining various life activities. The imbalance or disruption of neurotransmitters has been closely linked to various neurological disorders, including Parkinson's disease, anxiety, schizophrenia, depression, and Alzheimer's disease. Therefore, high-throughput detection and analysis of neurotransmitter-like substances have significant research implications for unraveling the pathogenesis, diagnosis, and treatment of neurological diseases.
- High-throughput: Utilizes a high-speed mass spectrometry platform with isotope internal standard validation, enabling simultaneous absolute quantification of various neurotransmitter-like substances.
- Professional service: Comprehensive after-sales service, supporting the process until data publication.
- Identification of neurotransmitter-like substances in samples such as tissues and cells.
- Investigation of the pathogenesis and early diagnosis of neurological disorders.
- Feed additives.
- Biomarkers for neurotoxicity of pollutants.