- Untargeted Metabolomics
- Lipidomics
- Targeted Metabolomics
- Functional Metabolomics
-
Proteomics
- Nanoparticle proteomics
- iTRAQ/TMT-based Proteomics Analysis
- Label free Quantitative Proteomics
- Protein Identification
- DIA proteomics
- Peptidomics
- Parallel Reaction Monitoring (PRM) Targeted Proteome
- Metpro -Ⅱ Protein-Metabolite Interactions
- Phosphoproteomics
- Acetylation Analysis
- Protein Ubiquitination Analysis
Tryptophan
Tryptophan is an essential amino acid involved in protein synthesis in the human body. It serves as a precursor to the important neurotransmitter serotonin (5-HT), contributing to promoting good sleep and combating depression. Tryptophan in food undergoes metabolism in various tissues such as the intestines, liver, and brain, producing various metabolites such as indole, indole derivatives, canine uric acid, 5-hydroxytryptamine, and melatonin. These metabolites play a role in several physiological and pathological processes, including depression, inflammatory bowel disease, and rheumatoid arthritis.
Tryptophan is a crucial nutritional supplement with significant roles in animal production. In animals, it can metabolize to produce essential precursors like canine uric acid, serotonin, and niacin, participating in various physiological metabolic processes. Due to the inability of animals to synthesize tryptophan internally, it has become an indispensable feed additive in modern poultry farming. Tryptophan is instrumental in improving the growth and production performance of poultry. It contributes to the renewal of plasma proteins, facilitates the action of riboflavin, and aids in the synthesis of niacin and hemoglobin, enhancing the animal's disease resistance.
Technical Advantages:
- Isotope internal standard quantification
- High-sensitivity mass spectrometry system
Application Directions:
- Neurodegenerative diseases
- Tumor metabolism
- Drug targets
- Research on the immune function of livestock and poultry
- Pest control
Collaborative Case:
"Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism." (2022) Journal of Agricultural and Food Chemistry. (Impact Factor=5.895) [Customer's Publication]
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