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Parallel Reaction Monitoring (PRM) Targeted Proteome

Parallel  reaction monitoring (PRM) is  an ion monitoring technique based on high-resolution and high-precision mass  spectrometry. The principle of this technique is comparable to SRM/MRM, but it  is more convenient in assay development for absolute quantification of proteins  and peptides. It is most suitable for quantification of multiple proteins in  complex sample with an attomole-level detection.


Advantages

High  sensitivity;

High  throughput;

Easier  to develop assay.


Application

Verification  of TMT differential protein;

Verification  of label-free differential protein;

Protein  and peptide absolute quantification;


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